P3442 & P0306 codes?

2012 RAM 1500
221,650 MILES • V8 • 4WD • AUTOMATIC
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ARRICK70
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This is on a 2012 5.7 hemi
Reman engine about 12k miles. Replaced the #6 injector. Have replaced coils,spark plugs,MDS solenoids & jumper wire.replaced VVT solenoid. Cam & crank sensors.Has a rebuilt PCM put in in August 2025. Ran great up until a cold spell we had in Indiana before Xmas. Then lights came on. Sometimes I can clear codes but still runs rough code returns at various times.
Jan 22, 2026 at 11:23 AM
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STRAILER
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Hello,

The first thing I would do is a compression test on #6, this video will show you how, you can rent a gauge set form the auto parts store for free to help with the test.

https://www.youtube.com/watch?v=KOxIm1F8AW0&pp=0gcJCYcKAYcqIYzv

P3442 - Cylinder 6 Deactivation/Intake Valve Control Circuit Performance
P0306 - Cylinder 6 Misfire

This test will tell us which way to go for the repairs. Let us know how it goes, Ken
Jan 23, 2026 at 11:36 AM
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ARRICK70
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I did that on 2,4,6,8 all came out the same.
Jan 23, 2026 at 12:10 PM
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STRAILER
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Okay, then the cylinder deactivation control solenoid has gone out. You will need to remove the intake manifold here is how to do the job which you will need a special tool for.

Install the Remover, MDS Solenoid 2028200090 (1) and securely tighten the retaining screw (2).Lightly tap on the top of the MDS solenoid removal tool with a rubber mallet or equivalent to break the seal. Pull vertically and remove the MDS solenoid(s). Clear the codes once completed. Check out the images (below). Let us know how it goes
Jan 24, 2026 at 10:38 AM
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ARRICK70
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The first thing I did was replace all the solenoids & jumper/harness. I've replaced the VVT solenoid as well.
Jan 25, 2026 at 6:14 AM
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STRAILER
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So to confirm you replace the "cylinder deactivation control solenoid" ?
Jan 25, 2026 at 8:36 AM
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ARRICK70
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Yes, all 4 of them.
Jan 25, 2026 at 10:40 AM
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STRAILER
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Okay, then the next step is to check the wiring, here is a guide to help you with the tests.

https://www.2carpros.com/articles/how-to-check-wiring

Here is the wiring diagrams to help test the ground and connection to the PCM. Check out the images (below). Please let us know what happens.
Jan 26, 2026 at 7:58 AM
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ARRICK70
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Sorry for late response,just worked on it over the weekend. I have checked all grounds & connections, they checked out good. Replaced #6 MDS s solenoid again just to be sure I didn't have a faulty one. Still have same issues.
I removed valve cover and replaced coils to run engine for a short period to watch rocker arms. The #6 intake isnt moving. So my question is now is it a collapsed lifter or
(signal/no signal)from PCM not activating #6 solenoid? There is times I've reset the codes and truck will idle & run good for a short period then the code will reappear and start running rough again. The video shows a short clip of the startup the top valve is #6 intake.
Feb 2, 2026 at 4:05 AM
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STRAILER
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Nice work, you have found the problem for sure. This can be one of two things either the lifter has gone bad and does not hold oil pressure or the camshaft has gone flat on the one lobe. You will need to remove the lifters but first the cylinder head will need to come off. Here is what the manual says about the problem.

NOTE: If excessive camshaft lobe wear/lifter wear (roller failure) has been identified, further inspection should be performed before attempting repair. Remove the Variable Valve Timing Solenoid (VVTS) and inspect the screens for metal debris. If no debris is found continue with camshaft and lifter replacement. If debris is found engine replacement is required.

Thanks for the video it helps us see what is going on. Sorry about the troubles, it happens.

Feb 2, 2026 at 9:13 AM