2003 Cadillac Deville Jerking on highway speeds

I have an 03 cadillac Deville base sedan. my car drives amazing in town and speeds below 55 mph. But when I get on a highway and I'm going around 65 mph or higher my car will jerks foward or backwards(I can't tell) It only does this every once in a while like every 10 minutes. But I feel like it does it more the farther I travel. I have two codes, the po101 and po410. I just replaced my mass air flow sensor but haven't driven on highway yet. I don't know if my po101 code has went off yet. I also think my acceleration isn't all that great.