engine is running lean and makes rattle noise under acceleration

I have replaced 02,maf, crank,cam and throttle position sensors, plugs, wires and even tried premium fuel.
When driving as long as you don't accelerate past 1/4 throttle it doesn't rattle like the timing is off. The car has no power and i've even verified that there is adequate fuel pressure i'm just curious if the ecu could be the culprit or any other suggestions