Cyl 2 and 3 misfire. What would be the most likely issue with the truck?

I have already heard all kinds of bad things of what it could be but not what it probably is. I just bought this truck a couple days ago and the scanner is showing cyl 2 and 3 misfire. Car doesnt seem to be running too hot or smoking. Seems to start right up most of the time but it does idle rough and stutter under medium to heavy accelleration if I start under 2000rpm instead of 2500 or higher. Does it alot on hils and 5th gear. Please help I have a child that rides in this and I work 33 miles away from my home and I can never catch a break with cars!